Association of Genetic Variation in theMETProto-Oncogene With Schizophrenia and General Cognitive Ability
نویسندگان
چکیده
منابع مشابه
Genetic Copy Number Variation and General Cognitive Ability
Differences in genomic structure between individuals are ubiquitous features of human genetic variation. Specific copy number variants (CNVs) have been associated with susceptibility to numerous complex psychiatric disorders, including attention-deficit-hyperactivity disorder, autism-spectrum disorders and schizophrenia. These disorders often display co-morbidity with low intelligence. Rare chr...
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چکیده ندارد.
No association between general cognitive ability and rare copy number variation.
There is increasing evidence for the role of rare copy-number variation (CNV) in the development of neuropsychiatric disorders. It is likely that such variants also have an effect on the variation of cognition in what is considered the "normal" phenotypic range. The role of rare CNV (>20 KB in length; frequency <5 %) on general cognitive ability is investigated in a sample of 800 individuals (m...
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ژورنال
عنوان ژورنال: American Journal of Psychiatry
سال: 2010
ISSN: 0002-953X,1535-7228
DOI: 10.1176/appi.ajp.2009.09050615